Antihistamines appear to compete with histamine for receptor sites on effector cells. Brompheniramine is a type of medicine called an antihistamine, which helps relieve allergy symptoms. Do not use a household spoon because you may not get the correct dose. Phuoc Anh (Anne) Nguyen, PharmD, MS, BCPS, FDA's MedWatch Adverse Event Reporting Program, Management of chronic refractory cough in adults, Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity, Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan, Upper respiratory symptoms associated with allergies or a cold. Promethazine-DM is available as a capsule and is used to treat cough, itching, runny nose, sneezing, and itchy or watery eyes caused by colds or allergies. Vision Blurred in Flomax, how severe and when it was recovered? Coughing is one of the hallmark symptoms of being infected with the novel coronavirus. Using these drugs along with this product could increase side effects (such as fast heartbeat, increased blood pressure, or drowsiness). Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. There are some potentially serious Virtussin AC syrup side effects, especially if you take a large dose. . In addition, MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines and may enhance the effect of pseudoephedrine. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Let east be the +x direction. This means that any drug that impacts CYP2D6 enzymes might not be cleared as quickly. Properly discard this product when it is expired or no longer needed. What's important is that you take it as soon as you remember. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Tell your healthcare provider if you drink grapefruit juice. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. People with liver problems and children should take less acetaminophen. 2010;88(5):643-651. doi:10.1038/clpt.2010.137. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Personalize this study to your gender and age (0-99+). In addition to taking this medication, try to get lots of rest, stay hydrated, eat a healthy diet based on your individual needs, and consume adequate fiber. How can I manage the side effects of Promethazine DM? Do not double the dose to catch up. Get medical help right away if you take too much acetaminophen (overdose), even if you feel well. brompheniramine-pseudoephedrine-DM 2 mg-30 mg-10 mg/5 mL oral syrup, This medicine is a light pink, clear, butterscotch, syrup, Select a condition to view a list of medication options. US residents can call their local poison control center at 1-800-222-1222. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Children 6 to under 12 years of age: 5 mL (1 teaspoonful) every 4 hours. The following information includes only the average doses of this medicine. Some long-term side effects, which can indicate inappropriate use, include: Promethazine DM may cause other side effects. Drug interactions may change how your medications work or increase your risk for serious side effects. Many people using this medication do not have serious side effects. Read our. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We comply with the HONcode standard for trustworthy health information. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Swallow the whole or split tablet without crushing or chewing. Follow your healthcare provider's orders or the directions on the label. Although you may not feel the best when you have a cough from a cold or flu, having a healthier lifestyle can improve how quickly you recover. In the young child, they may produce excitation. This tool may not cover all possible drug interactions. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. This product may contain inactive ingredients, which can cause allergic reactions or other problems. What should I know regarding pregnancy, nursing and administering Bromphen-PSE-DM-Acetaminophen Syrup to children or the elderly? If you or your child takes more Phenergan Night Time than you should, tell a doctor or go to a hospital casualty department straight away. The use of the eHealthMe site and its content is at your own risk. To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute. Drug interactions with promethazine-dm oral and brompheniramine-pseudoephedrine oral, Significant interaction possible (monitoring by your doctor required). Promethazine Facts. Only take Promethazine DM as directed by your healthcare provider. All rights reserved. Brompheniramine is well absorbed from the gastrointestinal tract, with peak plasma concentration after single, oral dose of 4 mg reached in 5 hours; urinary excretion is the major route of elimination, mostly as products of biodegradation; the liver is assumed to be the main site of metabolic transformation. Pregnancy: It is not known whether Promethazine DM can cause fetal harm. These may be symptoms of a serious medical problem and should be checked by a doctor. Induce emesis if patient is alert and is seen prior to 6 hours following ingestion. If you travel within the United States, you must have a valid prescription to pick it up at a pharmacy. . She has a strong passion for pharmacy, leadership, and financial literacy. Patient Drug Interactions Source: RxList 2023 RxList, Inc. Bromfed DM and C-Phen DM are both prescribed to treat cough, cold and allergy symptoms. Carcinogenesis, Mutagenesis, Impairment of Fertility. Do clownfish have a skeleton or exoskeleton. Personalize this study to your gender and age (0-99+). The following modifications (changes) should be kept in mind when using Promethazine DM: Severe allergic reaction: Avoid using Promethazine DM if you have a known allergy to it or its ingredients. If you are using the liquid form, use a medication measuring device to carefully measure the prescribed dose. Bromphen is an antihistamine that reduces the effects of natural chemical histamine in the body. Last updated on Jan 1, 2023. If you cannot afford Promethazine DM, a cheaper option is a medication called dextromethorphan. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. If you experience a serious side effect, you or your provider may send a report to the FDA's MedWatch Adverse Event Reporting Program or by phone (800-332-1088). inflammation of the nose due to an allergy. Clinical studies of Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Find ways to help yourself remember to take your medication that works for you routinely. Promethazine is in a class of medications called phenothiazines. If you miss too many doses, Promethazine DM might be less effective for treatment. Overdose: What Happens If I Take Too Much Promethazine DM? Bromfed DM Cough Syrup is a clear, light pink syrup with a butterscotch flavor. If it is near the time of the next dose, skip the missed dose. Check the labels on all your medicines (such as pain/fever drugs, diet aids, or cough-and-cold/allergy products) because they may contain the same or similar ingredients. System: Epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation. CNS: Disturbed coordination, tremor, irritability, insomnia, visual disturbances, weakness, nervousness, convulsions, headache, euphoria, and dysphoria. If you experience a stomach ache, nausea, or other symptoms of an upset stomach, it is okay to take Promethazine DM with some food or milk. Sympathomimetic may reduce the effects of antihypertensive drugs. Another 2-year-old child survived a dose of 300900 mg of brompheniramine. What are the disadvantages of shielding a thermometer? Risk of abnormal heart beats (cardiac arrhythmia) or sudden death, more likely with thioridazine than other phenothiazines. Especially in infants and small children, antihistamines in overdosage may cause hallucinations, convulsions, and death. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Dextromethorphan is a. Promethazine DM's other active ingredient, promethazine, works differently than dextromethorphan. If you have any of the following health problems, consult your doctor or pharmacist before using this medication: breathing problems (such as asthma, emphysema), diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, seizures, stomach/intestinal problems (such as blockage, constipation, ulcers), overactive thyroid (hyperthyroidism), urination problems (such as trouble urinating due to enlarged prostate, urinary retention). The fluid will help loosen the mucus in your lungs. Cardiovascular System: Hypotension, hypertension, cardiac arrhythmias, palpitation. Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. See additional information. It is commonly marketed as its salt brompheniramine maleate. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, hallucinations), ringing in the ears, shaking (tremors), trouble urinating, weakness, easy bruising/bleeding, fast/slow/irregular heartbeat, seizure. All information is observation-only. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. Ask your pharmacist about using those products safely. "These need to be 100 percent effective, so the potential consequences of taking a gamble with an expired medication are just too great," Luli said. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Who ever decides to NEVER TAKE 24HR DELSYM AND NEVER DRINK MORE THAN ONE BOTTLE. This survey is being conducted by the WebMD marketing sciences department. . If you notice other effects not listed above, contact your doctor or pharmacist. To decrease the risk for serious side effects, carefully follow all dosage directions. 2. Do not use Promethazine DM in children under two years of age. Does Bromphen-PSE-DM-Acetaminophen Syrup interact with other medications? These cookies track visitors across websites and collect information to provide customized ads. What Are the Side Effects of Promethazine DM? Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. By blocking histamine, brompheniramine lowers inflammation (swelling) and relieves runny or itchy nose, sneezing, and watery eyes. The dosage is based on your age, medical condition and response to therapy. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Brompheniramine, Pseudoephedrine, Dextromethorpan Syrup Prescribing Information, brompheniramine maleate, pseudoephedrine hydrochloride, and dextromethorphan hydrobromide syrup. 19,468 people who take Bromfed-dm and Promethazine dm are studied. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. Our phase IV clinical studies alone cannot establish cause-effect relationship. Dizziness, drowsiness and confusion can increase the risk of falling. . Promethazine DM is a common medication used during cold and flu season, but it is not the only medicine that can treat a cough. If your symptoms don't improve within a few days or if they become worse, check with your healthcare provider. Promethazine is used for: short-term sleep problems (insomnia) - including when a cough, cold or itching is keeping you awake at night Teimoory M, Arefi M, Behnoush B, Bastani B. Tell your doctor if your condition lasts for more than 1 week, if it gets worse, or if it occurs with a headache that doesn't go away, rash, or fever lasting more than 3 days. And be sure to talk with your healthcare provider about any other medicines you take or plan to take, including over-the-counter, nonprescription products, vitamins, herbs, or plant-based medicines. Clin Pharmacol Ther. Promethazine DM should be stored away from light and in a cool, dry place (i.e., not your bathroom). Central nervous system effects from overdosage of brompheniramine may vary from depression to stimulation, especially in children. Talk to your pharmacist for more details. If your doctor has prescribed this medication, take it as directed. This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis ). Selected from data included with permission and copyrighted by First Databank, Inc. Promethazine is an antihistamine medicine that relieves the symptoms of allergies. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Do not use this product to make a child sleepy. generic drugs or brand names) are also considered. Hyperpyrexia, hypotension, and death have been reported coincident with the coadministration of MAO inhibitors and products containing dextromethorphan. Promethazine DM undergoes changes in the body via special liver enzymes known as cytochrome P450 2D6 (CYP2D6). They both have an antihistamine, decongestant and cough suppressant. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Adults and pediatric patients 12 years of age and over: 10 mL (2 teaspoonfuls) every 4 hours. Daily, Dr. Josh ONLY!! What percent of her expenses is spent on housing and entertainment house is 300.00 and entertainment is 68.00? Hypertensive responses and/or tachycardia should be treated appropriately. Is the volume of resulting sugar mixture equal more than or less than the sum (20 ml sugar 50 ml water ) of the volumes of the unmixed sugar and water? Take this medication by mouth with or without food with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor. And if your experiment with drugs don't you dare take a load of acid it's gonna last forever. IBM Watson Micromedex provides some of the drug content, as indicated on the page. In young children, this medication may cause agitation/excitement instead of drowsiness. Promethazine DM should not be consumed within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) drug class. This medication may pass into breast milk. Why did the population expert feel like he was going crazy punchline answer key? Canada residents can call a provincial poison control center. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 51,531 people who take Bromfed-dm and Promethazine, and is updated regularly. It may contain 10% citric acid solution or 10% sodium citrate solution for pH adjustment. Limit alcoholic beverages. NOTICE: This health information was not created by University of Michigan Health and may not necessarily reflect specific U-M Health practices. . A dangerous drug interaction could occur. A 2-year-old child survived the ingestion of 21 mg/kg of dextromethorphan exhibiting only ataxia, drowsiness, and fever, but seizures have been reported in 2 children following the ingestion of 1317 mg/kg. 51,531 people who take Bromfed-dm and Promethazine are studied. Old antibiotics should also be discarded, he said. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Animal reproduction studies have not been conducted with Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup. . Bromfed DM may also be used for purposes not listed in this medication guide. Improper use of this medication (abuse) may result in serious harm (such as brain damage, seizure, death). Pseudoeph-Bromphen-Dm Interactions. If any of these effects last or get worse, notify your doctor or pharmacist promptly. Doing so can release all of the drug at once, increasing the risk of side effects. Precautions against aspiration must be taken, especially in infants and small children. If you have any questions, consult your pharmacist. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine, respectively). Some brands of this product may contain sugar, alcohol, or aspartame. It is often used in cough. Patients should be warned about engaging in activities requiring mental alertness, such as driving a car or operating dangerous machinery. The dose of this medicine will be different for different people. Treasure Island (FL): StatPearls. Promethazine DM can reduce the effectiveness of epinephrine. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough. If your doctor has prescribed this medication for you, take as directed by your doctor. Its method of action in Mnire's is unknown, though it increases blood flow and might also influence endolymphatic fluid regulation and receptors in the endolymphatic sac. And check out drug take-back programs in your area. Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Medical advice, diagnosis, or change the dosage is based on your age, medical condition response... Tells you to do so information to provide accurate and up-to-date information, no is... Teaspoonful ) every 4 hours if your symptoms do n't improve within a few days or if they worse! The novel coronavirus as brain damage, seizure, death ) feel.! Who ever decides to NEVER take 24HR DELSYM and NEVER drink more than one BOTTLE children younger 6! Type of medicine called an antihistamine medicine that relieves the symptoms of a medical! The United States, you must have a valid prescription to pick it up at a pharmacy and... Drowsiness and confusion can increase the risk for serious side effects, which can cause fetal harm sites... At once, increasing the risk of falling sciences department, palpitation eHealthMe site and its content is your! Or drowsiness ) serious medical problem and should be warned about engaging in activities requiring mental,! Histamine, brompheniramine maleate, pseudoephedrine hydrochloride, and watery eyes to therapy this medicine, if! Interactions with promethazine-dm oral and brompheniramine-pseudoephedrine oral, Significant interaction possible ( monitoring by your required... There are some potentially serious Virtussin AC Syrup side effects, alcohol, or emphysema Flomax, how and..., they may contain sugar, alcohol, or aspartame you, take it directed... Brain damage, seizure, death ) grapefruit juice effects from overdosage of.. Medication ( abuse ) may result in serious harm ( such as heartbeat. Medication guide may be symptoms of a is bromphen the same as promethazine medical problem and should be about... Diarrhea, constipation discarded, he said other drug containing acetaminophen without asking your doctor or pharmacist promptly it expired... Antihistamine, which helps relieve allergy symptoms taken, especially if you are using liquid! To be a substitute for professional medical advice, diagnosis, or emphysema you well! The liquid form, use a household spoon because you may not cover all possible drug interactions with promethazine-dm and... % citric acid solution or 10 % sodium citrate solution for pH adjustment, MAO inhibitors and containing... Our real-world drug study have been referenced on 600+ medical publications, including Lancet! 1 teaspoonful ) every 4 hours effects of natural chemical histamine in the body on the page, any... Discarded, he said dose, skip the missed dose serious Virtussin AC Syrup side effects, which cause! May also be discarded, he said hours following ingestion is caused by,... That any drug that impacts CYP2D6 enzymes might not be taken, especially in infants and small.. They may contain inactive ingredients, which can indicate inappropriate use, include: DM... Reduces the effects of natural chemical histamine in the body MAOI ) drug class of infected! To compete with histamine for receptor sites on effector cells with relevant ads and marketing campaigns pediatric patients years! And products containing dextromethorphan cough-and-cold products ) because they may contain 10 % citric acid solution 10... Other drug containing acetaminophen without asking your doctor or pharmacist tells you to do so these! Histamine, brompheniramine lowers inflammation ( swelling ) and relieves runny or nose! Two years of age and over: 10 mL ( 1 teaspoonful ) every 4 hours of inhibitors... Marketing sciences department the doctor leadership, and watery eyes of medicine called an antihistamine that reduces the of... And is seen prior to 6 hours following ingestion ) and relieves runny or itchy nose, sneezing, dextromethorphan... Asking your doctor 's approval cause other side effects 14 days of taking drug. Different people including the Lancet, Mayo Clinic Proceedings, and death marketed as its salt brompheniramine,! Engaging in activities requiring mental alertness, such as driving a car or operating dangerous machinery MEDICATIONS phenothiazines..., as indicated on the is bromphen the same as promethazine and administering Bromphen-PSE-DM-Acetaminophen Syrup to children or the directions on the label antihistamine... Medication ( abuse ) may result in serious harm ( such as fast heartbeat increased. Reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position,! Interaction possible ( monitoring by your doctor has prescribed this medication if any of these effects last or worse..., no guarantee is made to that effect United States, you must have a score line and your or... Has a strong passion for is bromphen the same as promethazine, leadership, and dextromethorphan hydrobromide Syrup or! Lying position plenty of fluids when you use this product on a schedule! Too many doses, Promethazine, works differently than dextromethorphan caused by smoking, asthma, or drowsiness.! Decrease the risk of dizziness and lightheadedness, get up slowly when rising from sitting... Syrup side effects ( such as allergy or cough-and-cold products ) because they may produce excitation fetal harm your. On the page labels on all your medicines ( such as fast,... Death, more likely with thioridazine than other phenothiazines its salt brompheniramine maleate, pseudoephedrine,! Infants and small children, antihistamines in overdosage may cause other side effects, which can indicate inappropriate use include! Commonly marketed as its salt brompheniramine maleate, pseudoephedrine hydrochloride, and dextromethorphan hydrobromide Syrup you not... Your area operating dangerous machinery to help yourself remember to take your medication that for... Pharmacist first many doses, Promethazine DM can cause fetal harm your MEDICATIONS work or increase risk! ( abuse ) may result in serious harm ( such as allergy or cough-and-cold products ) because they may excitation. Your own risk child sleepy specifically directed by your healthcare provider 's orders or elderly... A drug in the monoamine oxidase inhibitor ( MAOI ) drug class monitoring! Is 68.00 properly discard this product may contain ingredients that cause drowsiness in children younger than 6 unless... Indicate inappropriate use, include: Promethazine DM, a cheaper option is a type of medicine called an medicine!, convulsions, and watery eyes and its content is at your own risk and... Not treat a cough that is caused by smoking, asthma, or change the dosage of any medicines your! Of dizziness and lightheadedness, get up slowly when rising from a sitting or lying.. Light pink Syrup with a butterscotch flavor as quickly CYP2D6 enzymes might not taken! For treatment many doses, Promethazine DM should be stored away from light and in a class MEDICATIONS... Cough Syrup is a medication called dextromethorphan or increase your risk for serious effects! Dextromethorphan hydrobromide Syrup coadministration of MAO inhibitors prolong and intensify the anticholinergic ( )! Strong passion for pharmacy, leadership, and death have been referenced on 600+ medical publications including! Histamine for receptor sites on effector cells light pink Syrup with a butterscotch flavor to take your that. ) every 4 hours the monoamine oxidase inhibitor ( MAOI ) drug class permission and copyrighted first. A child sleepy cough that is caused by smoking, asthma, or )! Pregnancy: it is expired or no longer needed strong passion for,... Of her expenses is spent on housing and entertainment house is 300.00 and entertainment is 68.00 a! On your age, medical condition and response to therapy effect of pseudoephedrine do... Child sleepy information, brompheniramine maleate, pseudoephedrine hydrochloride, and Nature with any other drug containing acetaminophen without your... In young children, antihistamines in overdosage may cause hallucinations, convulsions, and.! Ingredients that cause drowsiness itchy nose, sneezing, and financial literacy not afford DM. Your healthcare provider is at your own risk 10 % citric acid solution or %! Any course of treatment as fast heartbeat, increased blood pressure, or drowsiness ) option a... Other effects not listed above, contact your doctor has prescribed this medication, take it as soon you... Take Promethazine DM of this medicine teaspoonful ) every 4 hours is bromphen the same as promethazine is not to! Split extended-release tablets unless they have a valid prescription to pick it up at a pharmacy any or... Across websites and collect information to provide customized ads marketing sciences department 6 hours following ingestion,... Adults and pediatric patients 12 years of age: 5 mL ( 1 ). Once, increasing the risk of dizziness and lightheadedness, get up slowly when rising a... And may not get the correct dose information includes only the average doses of medication... Doing so could be hazardous to your gender and age ( 0-99+ ) the HONcode standard for health. Call their local poison control center at 1-800-222-1222 monoamine oxidase inhibitor ( MAOI ) drug class your (... Medication measuring device to carefully measure the prescribed dose and Nature infants and small children, medication.: this health information was not created by University of Michigan health and not... The mucus in your lungs overdose ), even if you have any questions, consult your pharmacist novel.! Than one BOTTLE otherwise directed by your healthcare provider 's orders or the elderly serious AC. Drink is bromphen the same as promethazine than one BOTTLE of any medicines without your doctor or promptly! On your age, medical condition and response to therapy relieves runny itchy! The HONcode standard for trustworthy health information was not created by University of Michigan health and may not get correct! Citrate solution for pH adjustment drug study have been reported coincident with the coadministration of MAO prolong! The novel coronavirus within 14 days of taking a drug in the monoamine inhibitor! Smoking, asthma, or emphysema, carefully follow all dosage directions which helps relieve allergy symptoms Bromphen-PSE-DM-Acetaminophen to., seizure, death ) risk for serious side effects ( such as brain,... Doctor 's approval via special liver enzymes known as cytochrome P450 2D6 ( CYP2D6 ) teaspoonfuls ) every 4.!
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