Ever since this move, my dog is itching & scratching often. The itching and the lick granuloma healed. I started her on 1/2 tab once a day every day for the last month and 1/2. He was gone 6 days later. Im heartbroken that I didnt do my due diligence on this medication. Hes on IV fluids but not expected to live more than a week. The dose of Apoquel tablets is 0.18-0.27 mg/lb (0.4-0.6 mg/kg). Apoquel Side Effects. When I took him to the vet, he had 106 degree temp (above 102.5 in dogs is a fever) and they couldnt figure out where the infection was. These past 6 months have been H-ll with our beloved pets on these dangerous medications. Every dog that suffers from allergies may respond . I hope others do the same. Thank you all for comments. If youre wondering how I treat my dogs allergies, I focus on diet. Early Tuesday Nov 21 my husband woke me up to tell me that Ginny had let put a help and was very weak and could not stand up on her own. No more Apoquel for my dog! She was burping, licking her mouth, eating grass and her breath smelt very bad. Im praying Im not too late. VERY STRESSFUL, to get this large of a dog sedated and onto a table, he panicked as he was losing his ability to stand, the fear in his eyes made me lose it. As always, if you have any further questions or concerns, please do not hesitate to contact us. It was attached to the muscle and she didnt cut into it because of the location of the tumor. The bonding after reviving her is incredibly tight. We have a rescue dog, 3 yrs old now. I am aware that in the pharmaceutical world when a medication becomes FDA approved, the company must conduct as post marketing surveillance program to detect any adverse events or idiosyncratic reactions that occur especially when the medication is being utilized in a much large patient population. After allergy, blood and urine tests she put him on Apoquel, 2 times a day for 1 week and then one pill in morning. A dog who never once peed in the house, started having accidentswhen she was on a morning, noon, evening and bedtime schedule. I am concerned because I keep discussing apoquel with multiple vets taking care of him and I am told that is not the cause of his acute illness. seizure. Thank you for any help. Gabapentin should start to take effect fairly quickly, and relief should be noticed within one or two hours of administration. I wouldnt recommend it after our issues with it and reading others comments. My 10 year old Maltese 10 pound has had intermittent allergy problems his entire life. I forgot you add the above food mix to 3kg of chicken or turkey mince. Zyrtec, or Cetirizine, is a popular method of itch relief in our canine friends due to how few side effects there are, and the fact that Zyrtec does not cause drowsiness like other allergy medications. Within the first 12 hours he developed runny poop and lethargy. It can also be used for more long-term allergies but has varying results. The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of Apoquel. You may want to remember the golden rule..if you dont have anything nice to say, then dont say anything at all. Eating and drinking well but started soiling in the house. 1.7m dogs were tested. I fear for anyone giving this to their dog. But not at the cost of seizures. He is about 3 yrs old. I thought I had found relief for him and for us but obviously not. Research has found an ingredient known as praline-rich polypeptide (PRP) in bovine colostrum; it appears to be what is helping decrease the allergy symptoms. dog? In April he received Lyme vaccine and shortly thereafter developed skin infection requiring steroids. The vet was sure it was her thyroid and we did all the tests and they came back negative. Wow my eyes are wide. I know that an itching dog suffers, but I will try whatever I can to give her to be comfortable, and I know between the prednisone and apoquel she is probably being killed from the inside and I cannot do that to her. The Vitamin C dose is 100mg per 10lbs twice daily. See more at: http://news.zoetis.com/press-release/investors/zoetis-reports-fourth-quarter-and-full-year-2014-results#sthash.hYHWSMPk.dpuf, Revenue of nearly 5 billion dollarsa pretty heft marketing budget, along with an endless array of paid consultants/lobbyists to ensure that governing bodies dont over regulate and allow the company to keep on selling drugs, regardless of the occasional dead dog. Does zonisamide interact with my other drugs? You can check http://www.orthomolecular.org for more research and info. Too few veterinarians are explaining the risks. I cant wait for winter so I can see if I can take him off Apoquel and see if his weight goes down. She will pay for it! You wouldnt Inject AIDS in your child, that is what this stuff sounds like. He seemed to be cured. Sometimes he didnt even realize that he was urinating. I called the vet and they did blood work and checked him. She is allergic to beef, flax, white potatoe, corn and a few other things. We tried everything with no resolve. Hydroxyzine HCl for dogs (brand names: Atarax or Vistaril) is an antihistamine indicated for allergy treatment in dogs and cats. He is still dealing with the side effects of this medication. She has been on 3 primary seizure drugs used in humans for almost a year now. She sounds like a very sweet dog not making a mess for you. I will admit that I had no KNOWN adverse affects to the second dog and the drug did clear up the infections in both. Told vet and she took bloods so fingers crossed. The only thing the bw showed was that his body was basically starving. mini stroke. E-mail: rfisher1951@yahoo.com How long does it take for gabapentin to kick in for dogs? I took him to my vet who then sent me to Emergency. For a sonogram and X-rays that showed everything is normal. I have taken him off of it for 3 weeks now due to low funds, and was going to put him back on them this weekend. Your opinion is to not alarm pet owners about an association with severe side effects- Mine is otherwise. Stopped giving it to her and in 48 hours, she is spunky again. This drug should be taken off the market! He had been on it continually for about two/three years as I was I informed that there was no serious side effects and that it could be used for as long as it was working. I am so grateful to have finally found something that works and is healthy for her. Someone called us today to ask if we knew more of this approach for her dog. While it is not approved by the US-FDA for use in pets, veterinarians generally prescribe (Rx only) it as an extra-label drug. The vet never explained the side effects so I am thankful to you very thankful. Today we was at the vets, my Westie mix bison was given Apoquel 5.6grm and I gave him one today,after reading all your comments. Recently we moved to a different side of town in a metropolitan area and needed to find a new vet. (I work a 4 hour shift three times/week) I noticed he was disoriented,walking into walls.He was well enough to go for a short walk. We will continue with weekly medicated baths and if necessary will increase frequency of these. I went back to the vet and did an allergy test where we found out he is allergic to 19 things, including fish which was what he was eating. Tried Benydry but it only made him groggy. Again Please do not give your animal this medicine, Your email address will not be published. of the development of severe pyoderma (after day 19) and one dog withdrew because of the company and they said no connections. APOQUEL seems to be a wonder drug. Its poison to his body but he did stop scratching. We decided to continue the Apoquel until the next vet visit which was about 1 week later. She now urinates in the house. After one week on BID dosing he had a 5min seizure, I just chalked it up to stress. Has been on short term antibiotics and steroids for secondary skin infections. And one last comment, you claim that Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. Other than some itching she has always been healthy. with all I am reading, I am not sure if I will continue her on it or not. The vet recommended apoquel. Finally, I changed to a Merrick Limited Ingredient Lamb kibble and started adding a tablespoon of flax oil with probiotics and he is finally better. I also wonder if advantix 2 would be responsible for his rash. Saw right after I hit the Submit Comment button. This new vet prescribed Aproquel 16mg (twice daily 14 day supply) for a chronic allergy problem, we think from the cat. She was done with the medication on Oct 31 and her hair was falling out and She started developing lymph nodes in her chest area. It is a symptom of an underlying disease or condition. I am a regular pet owner with a 10 year old staffy with chronic allergies, but I would NEVER in my life give this drug to my dog. I read all the side effects from the study and didnt know what to do. Over the last month, I have watched my dog become extremely lethargic. He came to us with terrible skin allergies. You can continue to treat your dog with APOQUEL for as long as your veterinarian recommends. Died in hospital where we had to carry her. My poodle is masterful at holding it in emergencies when we get home longer than planned. The first 30 days there seemed to be no side effects, his appetite was good and it stopped the itching immediately upon the first dose he received. Oh and she totally ripped a couch pillow to shreds while we were out.. a couch she NEVER goes near! The potential for serious side effects is substantial, and that 1/3 of dogs did not respond in the study. Im not anti vet, I just think everyone needs to do their own research. and said everything is normal, probably will never happen again. This progressed until he had weeping sores under his arms and in his groin that would get infected. He may urinate a little longer than normal on Apoquel, but nothing to worry about yet here. Also she was not falling down for no reason. Am going to phone my vet in the morning and get their opinion. A vet gave my dog hydroxyzine because he was licking his paw a lot. She recently started peeing her bed and on the floor. I am still waiting for a call back. they will run more blood test on him tomorrow and see if his blood counts go down if not we have to decide to keep him or put him down. He is still itchy but will go back to Benadryl and an oatmeal bath weekly. it may even exacerbate cancer, Diarrhea, vomiting, (both w/ Customer: She's an American bulldog with horrible allergies. We are on the 16mg dose, but we break it in half and he is on 1/2 pill a day. It was like a miracle drug. Now, just do the rest of the world a favor and drop off the face of it and stop trying to scare people into doing what you want and believing what you think is correct. Zoetis and veterinarians should be held accountable, how can you be killing dogs with no compassion , no ethics, no nothing. Im not convinced and will certainly not be giving her anymore. These days, another type known as H2 antihistamines are commonly used. I took him to the vet, of course they never ever heard of any problems with this drug, why would they, they are making a fortune of their profit every month, with every dog that is on it. I cant say enough how appreciative I am this drug came along! Its nice to see her not so stressed out over scratching and with a beauriful full coat. Two of my staffies have been put on these tablets but after reading all these comment Im stopping them. I knew the potential for problems but was willing to do anything make her comfortable, and hoped that she would not show any negative effects. It may be used off label to treat skin infections in cats and urinary tract infections in dogs. In the article I list a number of alternative options to take- not requiring purchase of my scary supplement. Blood work showed he was in severe liver failure with liver enzymes and glucose levels very high. stand up hes so weak. 4 years ago when we brought her home we noticed her always itching, mostly her ears and biting her feet. Thanks for your advise earlier about the beta 3. Your email address will not be published. He is somewhat aggressive to a sweet little girl puppy that we got as a friend for him. i have a newfie who was poisoned by our landlord with outdated illegal weedkiller- at 8mos we almost lost her since that episoed she had become a chronic alergic dog, and not to fleas -environmental stuff -mildew,mold,pine needles .etc. These drugs were first discovered in the 1930s. The vet prescribed it and at first her allergies were better. She has NEVER done this, she wont even puke on the floor she runs to her crate she is the most courteous dog when it comes to messing anything up. I have a 5 yr old Yorkie/Poodle. It is disturbing to realize that others have had almost the same situation. I called the largest vet hospital in the area where they had a neurologist and got her in thru the ER. The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association. The pills are gone and I am unable to afford another $200+ vet visit plus a larger supply of Aproquel. I think it could be a very dangerous drug. Beware aspergillosis infections due to Apoquel Everyone! While the exact mechanism of action is not known, it is thought that Apoquel works by inhibiting the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response. isnt dying! Ollie is a sweet beautiful springer spaniel. I just had my 14 year old westie Flo on Apoquel for 26 days. Working very well for paw licking, but like others, he has to pee all the time and did so in the house yesterday (something he NEVER does). For slight allergies try otc antihistamines like Zyrtec. development of generalized demodicosis (after day 28). I took my 58# They are making Millions off this.?? If these sort of dermatologic/parasitic overgrowths occurred in humans from treatment with JK inhibitors, it would certainly prompt the FDA to take action to protect the patient population utilizing these medications from these severe adverse events (Answered 2023). With that, you will be able to give them the right dosage. A lot of dog owners are asking how much Apoquel their dog can take. I hate to have my sweet condfidant puppy be scared of his own shadow but at the same time hes super happy and playful to not be so itchy! The short answer is yes, it is safe to give your dog antihistamines alongside Apoquel. He will not walk againthey think the infection is in his spine now. He seemed afraid to move, as if it caused him pain. 3 Can be used for long-term maintenance or short-term therapy in dogs 12 months of age . Apoquel can be given with or without food. I was prescribed Apoquel for my 9 yr old pug with hot spots when I told my vet that I was concerned about the possible long-term effects of using Benedryl regularly. I will need to confine her if she continues to pee everywhere. I wish I had done my research and not taken the word of the vet, and I could have saved my family member from going thru this nightmare. My vet prescribed Apoquel for her and she immediately threw up and became very listless. Like a miracle her itching and inflamed skin improved. As a result, hydroxyzine pamoate is what doctors will prescribe to human patients to treat anxiety. IF your dog has allergies, he needs to be on these. She almost immediately stopped itching and I was delighted. Its only been one week so I dont expect a miracle. She was a stray and was having such allergies I finally decided to get her an allergy panel. Kudos to the very few who this drug has helped, I will not be taking that gamble. She was starting to feel a little better we thought but then she died the day after Christmas 2016. Her body was like a noodle. He was diagnosed with severe pancreatitis. I went to the FDA website and there is not one complaint that I can find from any vet or pet owner. We lost our Ginny girl. The medication is available in tablet form in the following doses: 10 mg; 25 mg; and 50 mg. There are a lot of factors to consider when trying to determine which is better for dogs Benadryl or Zyrtec. In some cases, more serious side effects may occur, such as infections or tumors. Dogs are able to take hydroxyzine. After an examination, they may deem it appropriate to prescribe an antihistamine as part of the treatment plan. So, does Apoquel stop itching? Just not for any on this wall including mine. As I write this I just want everyone to know.the drug may stop the itching as it did with my dog, but it allows the immune system to weaken and your dog wont be able to fight off the most basic thing: fungus. Ive made a official complaint against the vet that proscribed this poison only to be told that seizures are not a side effect of Apoquel the vets take no responsibility for my dogs death. Metronidazole (also known by the brand names Flagyl, Metizol, Protostat, Metrogel) is a strong antibiotic primarily used as an antidiarrheal to treat inflammation of the large intestine. Indianna veterinary dermatologist, Dr. Stacey L. Silva, DACVD, explains that while the active ingredient in Apoquel, oclacitinib, inhibits the production of histamines, its still unknown how the drug works to decrease inflammation and the itch associated with allergies. She had her own practice. Poor little guy. He is scheduled for more blood tests and an examination I called the vet but they said she must have eaten something to cause it. Carprofen was previously used in human medicine for over 10 years (1985-1995). Suddenly she was sneaking off to the back bedroom to go in-between. I am taking my dogs off of this. Cons: If your dog vomits after taking Apoquel , try giving it with some food or a meal after consulting with your vet. My Ginny was placed in ICU to help regulate her breathing. Unbelievable!!! I just think until you have an allergic dog, you are unaware how wide spread of a problem it is. And dont forget if youre at all concerned about your pets medication, then give your veterinarian a quick ring. She gave him different food and Hydroxizine, along with antinausea pills. It's also increasingly prescribed in combination with other medications for canine anxiety. We must consider what people are saying. Finally after several hours he ate his food and drank enough water. I dont want her to be itchy, but I also dont want her to be dead. He is now on phenobarbital for life because the seizures never went away. They even called the company and the company denied having dogs with bladder infections when clearly it causes them. As always, you should talk to your veterinarian before starting your dog on any new medication, even if its something as seemingly innocuous as Benadryl or Zyrtec. Can you give dogs Benadryl and Apoquel together? I would have preferred using prednisone as it has worked well in the past and he didnt need to take much. Now we will take her to Neurologist. 3.Regular bathing- of your dogs feet as he comes in from outside, and of your entire dog. Just please dont pump them with drugs, there is no magic pill but with research Im sure you too can find a natural solution that will help. Two days later he was at deaths door. My dog has very bad allergies. I didnt get a refill. In December 2017 we again returned to the veterinary center for evaluation and suggestions regarding these growths which continued to increase in number. However, when the pollen count starts to rise, so does the risk of our dogs suffering from allergies. The most horrible thing I was witness to.His right eye sunk in to his skull. My old boy Hamish is worse. They have been developed so as not to cause drowsiness. Your vet may prescribe it to relieve the symptoms of an allergic reaction. Ive been looking for others with the same diagnosis. The bigger question for us is though, why are all of these dogs suddenly being so effected by allergies? I even had to duct tape socks to his feet. diarrhea, vomiting, and lethargy that resolved spontaneously in 90% of cases and did not Remember just a 1/4 or less amount that a human would take for the vitamins unless I mentioned an amount the vet gave me. 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